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Introduction to Part II: Program, Control, and Create

Mackenzie Morehead

21 Nov 2023

Read next section: RNA & gene therapies

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The Fickleness of Scaling Laws

The Fickleness of Scaling Laws

Or, the Foundations of Foundation Models Nothing has defined tech in the last five years more than scaling laws. LLMs demonstrated consistent returns to scaling to dumbfounding sizes and cracked the positive feedback loop of scale to larger size to make a more useful product to raise and make more
19 Feb 2026 24 min read
Ozempic for Sleep

Ozempic for Sleep

Pharma and biotech do not take sleep seriously enough. All neurological disorders are sleep disorders. Alzheimer’s, Parkinson’s, depression, autism, schizophrenia, Huntington’s, epilepsy, bipolar disorder, etc. are all intimately intertwined with sleep. Recent research even suggests it causes or precedes many.  Moreover, beyond GLP-1s, sleep is one of
17 Dec 2025 10 min read
What To Do if Energy Gets Cheap?

What To Do if Energy Gets Cheap?

Solar has long been marching down an exponential, improving at a learning rate of 25% per doubling for 70 years. Their cost has now fallen by 1,000,000x cumulatively. A scarce few physical technologies like transistors can boast such durable scaling “laws”.  And yet, the global LCOE for solar
09 Dec 2025 18 min read
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